id author title date pages extension mime words sentences flesch summary cache txt cord-320158-6dh9e5rg Hansen, Richard Adaptations to the current ECCO/ESPGHAN guidelines on the management of paediatric acute severe colitis in the context of the COVID-19 pandemic: a RAND appropriateness panel 2020-09-01 .txt text/plain 5593 284 37 CONCLUSION: Our COVID-19-specific adaptations to paediatric ASC guidelines using a RAND panel generally support existing recommendations, particularly the use of corticosteroids and escalation to infliximab, irrespective of SARS-CoV-2 status. [10] [11] [12] Panellists rated the appropriateness of specific interventions at various time points during a patient's admission with ASC (admission, first-line therapy, rescue therapy, continued medical therapy on discharge and surgery) in the context of their SARS-CoV-2 swab status and the presence or absence of symptoms or signs of COVID-19 infection. After the second round of voting, agreement was present for all scenarios (DI<1) except two, both relating to SARS-CoV-2positive patients with symptoms or signs of infection; the use of ciclosporin with corticosteroids as rescue therapy and the use of prophylactic anticoagulation after discharge A detailed list of all scenarios, complete with median score, appropriateness rating and DI is shown in online supplementary table 2. ./cache/cord-320158-6dh9e5rg.txt ./txt/cord-320158-6dh9e5rg.txt