id author title date pages extension mime words sentences flesch summary cache txt cord-320460-7b8lqhl8 Shapira, G. Ethnic differences in SERPINA1 allele frequencies may partially explain national differences in COVID-19 fatality rates 2020-08-26 .txt text/plain 1969 140 46 We present preliminary evidence that these variations may in part reflect ethnic differences in the frequencies of polymorphic alleles of SERPINA1, coding for alpha-1 antitrypsin, the major blood serine protease inhibitor. We examined if population variations in human serine protease inhibitor (serpin) genes may help explain the lower COVID-19 infection rates and fatalities in East and Southeast Asia and Sub-Saharan Africa, compared to other regions. . https://doi.org/10.1101/2020.08.24.20179226 doi: medRxiv preprint carrier frequency of alpha-1 antitrypsin deficiency PiZ and PiS alleles in East and Southeast Asian and Sub-Saharan African countries may help explain the lower COVID-19 infection and mortality rates in these regions. It is made available under a perpetuity.is the author/funder, who has granted medRxiv a license to display the preprint in (which was not certified by peer review) preprintThe copyright holder for this this version posted August 26, 2020. ./cache/cord-320460-7b8lqhl8.txt ./txt/cord-320460-7b8lqhl8.txt