id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320822-etibcspx	Wright, Franklin L.	Fibrinolysis Shutdown Correlates to Thromboembolic Events in Severe COVID-19 Infection	2020-05-15		.txt	text/plain	2420	128	38	CONCLUSIONS: Fibrinolysis shutdown, as evidenced by elevated D-Dimer and complete failure of clot lysis at 30 minutes on thromboelastography, predicts thromboembolic events and need for hemodialysis in critically ill patients with COVID-19. While not significant, thrombotic stroke rate was also increased from 7% to 30% (p=0.274 In the trauma population, hypercoagulable TEG parameters predict venous thromboembolism (VTE) 2.4 -6.7 fold higher based on higher maximum amplitude (MA) parameters despite appropriate prophylactic anticoagulation [16] [17] [18] [19] . Elevated D-dimer levels were also associated with potential micro-thrombotic disease leading to Recently, acute fibrinolysis shutdown has been demonstrated in early sepsis and found to correlate to increased morbidity and mortality 32 . A TEG LY30 of 0% and a D-dimer of greater than 2600 ng/ml together suggest complete fibrinolysis shutdown and markedly elevated risk of renal failure, VTE, and thrombotic events.	./cache/cord-320822-etibcspx.txt	./txt/cord-320822-etibcspx.txt