id author title date pages extension mime words sentences flesch summary cache txt cord-321387-5epa1bb8 Altuntas, Fevzi Convalescent Plasma Therapy in Patients with COVID-19 2020-09-19 .txt text/plain 2381 158 60 In this study, we aim to investigate the efficacy of convalescent plasma (CP) in the treatment of severe and critically ill patients diagnosed with COVID-19. Administration of CP 20 days after the COVID-19 diagnosis or COVID-19 related symptoms were associated with a higher rate of MV support compared with the first 3 interval groups (≤5 days, 6-10 days, 11-15 days) (p=0.001) CONCLUSION: CP therapy seems to be effective for a better course of COVID-19 in severe and critically ill patients. From the Republic of Turkey, Ministry of Health database, severe or critically ill COVID-19 patients who received anti-SARS-CoV-2 antibody-containing CP along with the antiviral treatment (n = 888) were selected and included in the study. Therefore, patients who received CP treatment in the first 5 days of their COVID-19 diagnosis may represent a rapidly worsening clinical course as they became severely or critically ill in the first 5 days of the disease. ./cache/cord-321387-5epa1bb8.txt ./txt/cord-321387-5epa1bb8.txt