id author title date pages extension mime words sentences flesch summary cache txt cord-321412-6g3obmzc Khamis, Faryal Therapeutic Plasma Exchange in Adults with Severe COVID-19 Infection 2020-06-23 .txt text/plain 3142 168 55 Therapeutic plasma exchange (TPE) was performed on patients admitted to intensive care unit (ICU) with confirmed or imminent acute respiratory distress syndrome (ARDS) or severe pneumonia. CONCLUSIONS: The use of TPE in severe COVID-19 patients has been associated with improved outcomes, however, randomized controlled clinical trials are warranted to draw final conclusive findings. TPE was given after 7 and up to 14 days of illness to adult patients, 18 years of age, with laboratory confirmed COVID-19 disease who were admitted to intensive care unit (ICU) with confirmed or imminent respiratory failure and any one of the following conditions (ARDS Definition Task Force, 2012): The study enrolled a total of 31 COVID-19 patients fulfilling the WHO case definition (WHO Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance, 25 January 2020, 2020) with an overall mean age of 51  15 years (range: 27-76 years) and 90% (n = 28) were males. ./cache/cord-321412-6g3obmzc.txt ./txt/cord-321412-6g3obmzc.txt