id author title date pages extension mime words sentences flesch summary cache txt cord-321768-oevswvvd Duan, Ya-qi Deficiency of Tfh Cells and Germinal Center in Deceased COVID-19 Patients 2020-08-07 .txt text/plain 2307 125 51 In this study, we examined the immune cell compositions in the lung tissues and hilar lymph nodes using immunohistochemistry on 6 deceased COVID-19 patients and 4 focal organizing pneumonia (FOP) patients who underwent lung surgery and served as controls. In contrast to the FOP patients, Tfh cells and germinal center formation were largely absent in the draining hilar lymph nodes in the deceased COVID-19 patients. Characterization of compositions of the immune cells within the lung tissues and draining hilar lymph nodes from the postmortem specimens might provide valuable insights on how the immune responses in the deceased patients were dysregulated and offer new strategies for treatment. To gain insight into the human immune responses during a fatal SARS-CoV2 infection, we performed postmortem autopsy studies of the immune cell compositions within the lung tissues and hilar lymph nodes using immunohistochemistry on 6 deceased COVID-19 patients, and 4 FOP patients who underwent lung surgery served as controls. ./cache/cord-321768-oevswvvd.txt ./txt/cord-321768-oevswvvd.txt