id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322471-wt7zt6a8	Raparelli, Valeria	Sex differences in clinical phenotype and transitions of care among individuals dying of COVID-19 in Italy	2020-10-16		.txt	text/plain	4039	196	45	METHODS: A retrospective analysis was performed to assess if sex differences exist in the clinical manifestations and transitions of care among hospitalized individuals dying with laboratory-confirmed SARS-CoV-2 infection in Italy (February 27–June 11, 2020). As part of the surveillance activity of the Italian National Institute of Health (Istituto Superiore di Sanità-ISS), a sex-stratified analysis was performed with the aim to look for differences in the presentation and clinical course among women and men who died with COVID-19 in Italy. To understand the complexity and the intersection of the clinical features of individuals dying from COVID-19 according to sex, a multivariable analysis adjusted for age, comorbidities, symptoms at onset, treatment received, in-hospital complications, and length of stay was performed (Fig. 1) . A recent registry-based analysis of 4842 COVID-19 Danish hospitalized patients with COVID-19 reported an excess risk (on average more than 50%) of adverse outcomes, including mortality and ICU admission in men versus women regardless of age and comorbidities, questioning the central role of advanced age and multi-morbidities in explaining the male predominance [33] .	./cache/cord-322471-wt7zt6a8.txt	./txt/cord-322471-wt7zt6a8.txt