id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-323631-r31sfq90	Edul, Vanina Siham Kanoore	Microcirculation alterations in severe COVID-19 pneumonia	2020-10-17		.txt	text/plain	786	62	41	PURPOSE: To assess the presence of sublingual microcirculatory and skin perfusion alterations in COVID-19 pneumonia. Compared to previously reported normal values, total and perfused vascular density (21.9 ± 3.9 and 21.0 ± 3.5 mm/mm(2)) and heterogeneity flow index (0.91 ± 0.24) were high; and the proportion of perfused vessels (0.96 ± 0.03), microvascular flow index (2.79 ± 0.10), and red blood cell velocity (1124 ± 161 μm/s) were reduced. Sublingual microcirculation was characterized by decreases in the proportion of perfused vessel and flow velocity along with high vascular densities. Microvascular thrombosis has recently been diagnosed in patients with COVID-19, and it has been proposed to mediate the pathogenesis of organ injury in this disease [1] . Recently, sublingual microcirculatory abnormalities were shown in 12 patients with COVID-19 pneumonia [5] . Thus, our goal was to assess the characteristics of sublingual microcirculation and skin perfusion in patients with acute respiratory distress syndrome (ARDS) secondary to COVID-19.	./cache/cord-323631-r31sfq90.txt	./txt/cord-323631-r31sfq90.txt