id author title date pages extension mime words sentences flesch summary cache txt cord-324669-qca0uwxo Radermecker, Coraline Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19 2020-09-14 .txt text/plain 4883 261 43 title: Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19 Neutrophil extracellular traps (NETs) can contribute to inflammation-associated lung damage, thrombosis, and fibrosis. Our study reports that NETs infiltrate distinct compartments and lesions in the lungs of COVID-19 patients with a fatal outcome. Altogether, our study supports the idea that targeting NETs in COVID-19 patients may help the clinical management of severe forms of COVID-19 by alleviating thrombotic events, excessive tissue-damaging inflammation, fibrosis, and airway obstruction. Online supplemental material Fig. S1 shows microscopy pictures of immunofluorescence lung sections from non-COVID-19 patients stained with DAPI, anti-MPO, and anti-Cit-H3 antibodies. Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome COVID-19: Role of neutrophil extracellular traps in acute lung injury (C) Representative confocal microscopy pictures of immunofluorescence staining of lung sections from non-COVID-19 patients (MPO [red] and Cit-H3 ./cache/cord-324669-qca0uwxo.txt ./txt/cord-324669-qca0uwxo.txt