id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324776-upfguze6	Zhang, Peihua	Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates	2020-10-17		.txt	text/plain	1811	107	53	title: Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates This study aimed to evaluate the association of interleukin-6 (IL-6) level with the poor outcomes in coronavirus disease 2019 (COVID-19) patients by utilizing a meta-analysis based on adjusted effect estimates. The results based on random-effects model indicated that elevated value of IL-6 was significantly associated with adverse outcomes in patients with COVID-19 (pooled effect = 1.21, 95% CI 1.13–1.31, I(2) = 90.7%). Therefore, it is necessary to evaluate the association of IL-6 level with the adverse outcomes of COVID-19 patients by utilizing a meta-analysis on the basis of adjusted effect estimates. The results of subgroup analysis only based on prospective studies showed that elevated IL-6 values were also significantly associated with adverse outcomes in COVID-19 patients (pooled effect = 1.07, 95% CI 1.01-1.14) (Fig. S2b) .	./cache/cord-324776-upfguze6.txt	./txt/cord-324776-upfguze6.txt