id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-326210-216atclj	Sturmberg, Joachim P.	COVID‐19 – how a pandemic reveals that everything is connected to everything else	2020-07-06		.txt	text/plain	2758	161	50	Each of these approaches has its own dynamics affecting individuals, communities, health systems, the economy, and the nation as a whole-new patterns emerge that become understandable with increasing knowledge (Figure 1 ). The emerging dynamics then shift the system to a new-stable or unstable-state, where the relationships and the interactions between the systems' agents have permanently changed within the context of a different set of constraints. For example, imposing community-wide (self-) isolation entails that "almost all activities stop", destroying the economy and resulting in high unemployment, poverty, and increasing disease burden, while implementing strategies to slow down the spread of infection will not guarantee that we will not overwhelm health systems or stabilize the pandemic. The detrimental effects of the COVID-19 pandemic on the economy, besides that of the disease fears, increases the dysregulation of the physiological stress responses that, in turn, result in the dysregulation of upstream metabolic pathways, which have longterm health consequences far beyond the direct effects of the pandemic to such a degree that the agents at other levels cannot do the work that needs to be done.	./cache/cord-326210-216atclj.txt	./txt/cord-326210-216atclj.txt