id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327028-dbvucvy3	Zhang, Cantong	Controversial treatments: An updated understanding of the coronavirus disease 2019	2020-04-10		.txt	text/plain	1898	123	40	To reduce the case‐fatality rate among coronavirus disease 2019 patients, we should not ignore the complications, such as RNAaemia, acute respiratory distress syndrome, and multiple organ dysfunction. To help understand the advantages and limitations of differential treatments, we provide a timely review and discuss the complications and corresponding major treatments, especially controversial ones such as antiviral therapy (remdesivir, ribavirin, and chloroquine), glucocorticoid therapy, extracorporeal support including an artificial liver system, and extracorporeal membrane oxygenation based on available evidence. Furthermore, we list a table to conclude the mechanism, advantages, and limitations for different treatments mentioned in this review (Table 2) The mechanism of remdesivir against the virus showed that the drug effectively inhibited the Ebola virus RNA-dependent RNA polymerase (RdRp) complex. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China	./cache/cord-327028-dbvucvy3.txt	./txt/cord-327028-dbvucvy3.txt