id author title date pages extension mime words sentences flesch summary cache txt cord-327165-vlyfbiem Montorfano, Lisandro Colorectal surgery obesity-related morbidity during COVID-19 2020-07-09 .txt text/plain 2350 143 45 The purpose of this report was to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 pneumonia who received empiric Tocilizumab. The purpose of this case report was to analyze the risks of acute large bowel perforation after using Tocilizumab empirically for COVID-19 pneumonia in morbidly obese patients and discuss the appropriate management of this adverse event. However, to the best of our knowledge, this is the first report describing bowel perforation in a critically ill COVID-19-positive patient receiving empiric Tocilizumab. Our patient received both medications before the acute large bowel perforation occurred, because she received empiric Tocilizumab for COVID-19 pneumonia and Dexamethasone for several days for pharyngeal edema. This case report describes a rare case of colonic perforation in a critically ill, morbidly obese patient with COVID-19 pneumonia on empiric Tocilizumab therapy. ./cache/cord-327165-vlyfbiem.txt ./txt/cord-327165-vlyfbiem.txt