id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327827-oliw4ee5	Sweid, Ahmad	Letter: Thrombotic Neurovascular Disease in COVID-19 Patients	2020-06-04		.txt	text/plain	1050	73	51	1, 2 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor. 3, 4 Additionally, epidemiological data demonstrated increased mortality due to cardiovascular and cerebrovascular diseases during flu pandemics due to a hypercoagulable state. 5, 6 The triad of neuroinvasion of SARS-CoV-2, induction of hypercoagulable state, [5] [6] [7] [8] [9] and the inhibition of ACE2 blocking the formation of Angiotensin (1-7) serve as the pathophysiology for neurovascular insults. 3, 4 We present a case series of coronavirus disease 2019 (COVID-19) patients from 2 health systems developing cerebrovascular insult. Fourteen patients were identified with the diagnosis of cerebrovascular insult and COVID-19 infection. Medical charts were queried for baseline patient characteristics, comorbidities, COVID-19 symptoms, duration between COVID-19 symptoms and the neurological manifestation, cerebrovascular insult, National Institutes of Health Stroke Scale (NIHSS) at presentation, procedure details, and mortality. Moreover, cerebrovascular insult was the primary manifestation of COVID-19 in patients who did not have the fulminant virus manifestations present.	./cache/cord-327827-oliw4ee5.txt	./txt/cord-327827-oliw4ee5.txt