id author title date pages extension mime words sentences flesch summary cache txt cord-328220-toeq4xq0 Smith, Kelly Practical Considerations in Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID-19 2020-07-06 .txt text/plain 3207 168 40 Areas of management requiring clinical equipoise include agent selection and dosing, continuation vs interruption of home oral anticoagulant therapy during hospital admission, and postdischarge VTE prophylaxis. CONCLUSION: Practical guidance on anticoagulation considerations and dosing suggestions are provided to assist clinicians faced with challenging anticoagulation-related situations in caring for hospitalized COVID patients until formal evidence-based guidelines become available. [8] [9] [10] [11] [12] Areas of current clinical uncertainty include dose and agent of choice, continuation vs interruption of home oral anticoagulant therapy while admitted, and postdischarge VTE prophylaxis. Upon review of the available evidence, we believe that clinicians may wish to consider a 3-tiered approach to stratifying anticoagulation intensity ( Figure 1 ), with consideration of the aforementioned factors to guide and assist in decision making. A patient may be categorized into tier II based on acuity and/or VTE risk factors (eg, a patient who is on a general medical floor but clinically deteriorating, with an upward trend in inflammatory marker and/or D-dimer levels). ./cache/cord-328220-toeq4xq0.txt ./txt/cord-328220-toeq4xq0.txt