id author title date pages extension mime words sentences flesch summary cache txt cord-329628-2bqrutrt Zhao, Xiaofang Early decrease in blood platelet count is associated with poor prognosis in COVID-19 patients—indications for predictive, preventive, and personalized medical approach 2020-05-14 .txt text/plain 3428 212 54 title: Early decrease in blood platelet count is associated with poor prognosis in COVID-19 patients—indications for predictive, preventive, and personalized medical approach The platelet count reflects the thrombocyte turnover, acting as a sensitive indicator of illness severity that is of great clinical utility to monitor a quickly changing health condition of patients affected by aggressive viral infections. In fact, several clinical observational studies have found that COVID-19 patients had lower counts of platelet [8, 9, 12, [14] [15] [16] . This study aimed to investigate the difference in platelet count between survivors and non-survivors among COVID-19 patients. Finally, the relationship between early (0-7 days) changes in platelet count and death in 532 COVID-19 patients derived from a generalized additive mixed model (GAMM) was analyzed ( Table 3) . Our data indicate that platelet count has important information, which could be used for improved prediction, patient stratification (moderate vs high severity of the disease), and personalized prevention needed for the COVID-19-infected individuals, in order to save lives and economical resources. ./cache/cord-329628-2bqrutrt.txt ./txt/cord-329628-2bqrutrt.txt