id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-329912-4tbwk8cp	Loveday, Chey	Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study	2020-08-24		.txt	text/plain	5322	274	46	OBJECTIVE: To evaluate the impact of faecal immunochemical testing (FIT) prioritisation to mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait (2WW)) pathway consequent from the COVID-19 pandemic. FIT triage of symptomatic patients in primary care could streamline access to colonoscopy, reduce delays for true-positive CRC cases and reduce nosocomial COVID-19 mortality in older true-negative 2WW referrals. 2 3 Reports of high rates of nosocomial COVID-19 infection and mortality present a dilemma to primary care physicians regarding the risk-benefit trade-off of investigatory referral into hospital for older patients with symptoms suggestive of cancer. We estimate that even short delays in the pathway to CRC treatment will result in significant mortality and lost LYs. Provided nosocomial infection rates are controlled, there is net survival benefit in all age groups for prompt investigatory referral for colonoscopy.	./cache/cord-329912-4tbwk8cp.txt	./txt/cord-329912-4tbwk8cp.txt