id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-330151-7ylnxtcq	Fang, Shilin	Decreased complement C3 levels are associated with poor prognosis in patients with COVID-19: a retrospective cohort study	2020-10-05		.txt	text/plain	865	66	50	title: Decreased complement C3 levels are associated with poor prognosis in patients with COVID-19: a retrospective cohort study METHODS: The levels of total immunoglobulins (IgG, IgM, IgA, and IgE), complement (C3, C4) results were retrospectively analyzed in COVID-19 patients. Multivariable regression showed increasing odds of in-hospital death associated with older age (HR: 1.099; 95%CI: 1.057-1.143; p < 0.0001), d-dimer greater (HR: 1.294; 95%CI: 1.138-1.473; p < 0.0001) and decreased complement C3 level (HR: 0.073; 95%CI: 0.007-0.722; p = 0.025) on admission. Finally, in survival COVID-19 patients whose humoral immunity was re-examined, C3 levels tended to increase, while in non-survivors it decreased. Risk Factors Associated With Acute Respiratory Distress Syndrome 330 and Death in Patients With Coronavirus Disease Complement associated microvascular injury and thrombosis in the pathogenesis of 394 severe COVID-19 infection: A report of five cases, Translational research : the journal of 395 laboratory and clinical medicine	./cache/cord-330151-7ylnxtcq.txt	./txt/cord-330151-7ylnxtcq.txt