id author title date pages extension mime words sentences flesch summary cache txt cord-330159-vm30ohrb Beretta, Federica Practical Considerations for the Management of Cushing's Disease and COVID-19: A Case Report 2020-09-11 .txt text/plain 2747 141 41 Conclusion: Adrenal insufficiency might be a clinical challenge that needs a prompt treatment also in CS patients during COVID-19 infection. All antidiabetic medications were suspended in the early days of hospitalization owing to the good glucose control; however, in the mid of hospitalization, we observed a persistence of symptomatic hypotension with hypoglycemia, and in suspicion of adrenal insufficiency (blood pressure 90/60 mmHg), we withdrew metyrapone and i.v. hydrocortisone 50 mg was promptly prescribed (Figure 1) . CS patients might develop a severe form of COVID-19 infection, considering that the major comorbidities associated with COVID-19 mortality are hypertension, diabetes, previous heart disease, and cerebral infarction (10) . → Adrenal insufficiency might be a clinical challenge that needs a prompt treatment also in CS patients during COVID-19 infection. → Consider the possibility to titrate or temporary halt medical therapies for CS in the context of COVID-19 infection in order to avoid adrenal insufficiency. ./cache/cord-330159-vm30ohrb.txt ./txt/cord-330159-vm30ohrb.txt