id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-330655-crfj5adf	Haider, Asim	COVID-19 and the Brain: Acute Encephalitis as a Clinical Manifestation	2020-10-03		.txt	text/plain	1597	92	44	The researchers confirmed the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the cerebrospinal fluid (CSF) by genome sequencing [4] . Due to suspicion of COVID-19-related encephalitis, the patient received two doses of tocilizumab (400 mg each) followed by intravenous (IV) immunoglobulin (1 g/kg) for five days. A study that specifically investigated this issue documented that 36% of the hospitalized patients with a confirmed diagnosis of an acute respiratory syndrome from COVID-19 infection had some neurological manifestations. The exact mechanism by which COVID-19 infects CNS is not well-understood due to a lack of experimental data, but it is considered a mutation of the Middle East respiratory syndrome (MERS) virus and severe acute respiratory syndrome (SARS) virus [3] . Two case series involving CSF analysis data from 12 patients reported that the CSF had no white blood cells and the PCR assay for SARS-CoV-2 was negative in all the patients [9, 10] . Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study	./cache/cord-330655-crfj5adf.txt	./txt/cord-330655-crfj5adf.txt