id author title date pages extension mime words sentences flesch summary cache txt cord-331030-3icwei3e Saleknezhad, N. COVID-19 and heart medications: What's the connection? 2020-08-26 .txt text/plain 2728 195 58 Aim: To determine association between clinical outcome of COVID-19 and prior usage of cardiovascular and metabolic drugs, including, Aspirin, ACEIs, ARBs, Clopidogrel, metformin, and Statins. Therefore, we conducted a study based on our registry of COVID-19 patients to evaluate the effect of those drugs, which are widely used in chronic diseases such as hypertension, diabetes mellitus and ischemic heart disease, on the clinical outcome and mortality rate of the patients inflicted with the novel coronavirus. With regards to the clinical manifestations of the disease it is noteworthy that, as our data suggests, previous use of aspirin is correlated with decreased level of consciousness upon admission (p < 0.05), and on the other hand, patients who were under treatment with ACEIs are more probable to be symptom-free (p < 0.05). The outcome of patients, including mortality, ventilation requirement and ICU admission showed no correlation with receiving ARBs, ACEIs, statins, or Clopidogrel. ./cache/cord-331030-3icwei3e.txt ./txt/cord-331030-3icwei3e.txt