id author title date pages extension mime words sentences flesch summary cache txt cord-331947-s97h7sxj Deng, H.-J. Cytokine biomarkers of COVID-19 2020-06-03 .txt text/plain 3950 233 52 Cytokines that can classify populations in different states of SARS-CoV-2 infection were first screened in cross-sectional serum samples from 184 subjects by 2 statistical analyses. Three cytokines, M-CSF, IL-8 and SCF, which were clustered into 3 different correlation groups and had relatively small fluctuations during SARS-CoV-2 infection, were selected for the construction of a multiclass classification model. Further searching led to a single cytokine, hepatocyte growth factor (HGF), which classified severe from nonsevere COVID-19 patients with a sensitivity of 84.6% and a specificity of 97.9% under a cutoff value of 1128 pg/ml. . https://doi.org/10.1101/2020.05.31.20118315 doi: medRxiv preprint Cross-sectional serum samples were obtained from 184 subjects, including 37 healthy controls, 37 asymptomatic individuals infected with SARS-CoV-2 confirmed by RT-PCR, 97 nonsevere or moderate COVID-19 inpatients, and 13 severe COVID -19 patients. . https://doi.org/10.1101/2020.05.31.20118315 doi: medRxiv preprint CoV-2 infection, including healthy controls and asymptomatic infection, nonsevere and severe COVID-19 patients, might be involved in the immune or inflammatory response induced by the virus. ./cache/cord-331947-s97h7sxj.txt ./txt/cord-331947-s97h7sxj.txt