id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-332153-fczf3lzc	Azkur, Ahmet Kursat	Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19	2020-05-12		.txt	text/plain	6181	439	50	In this review, we aim to improve our understanding on the immune response and immunopathological changes in patients linked to detoriating clinical conditions such as, cytokine storm, acute respiratory distress syndrome, autopsy findings and changes in acute phase reactants and serum biochemistry in COVID‐19. The IgM, IgA and IgG type virus‐specific antibodies levels are important measurements to predict population immunity against this disease and whether cross‐reactivity with other coronaviruses is taking place.High viral‐load during the first infection and repeated exposure to virus especially in healthcare workers can be an important factor for severity of disease. It should be noted that many aspects of severe patients are unique to COVID‐19 and are rarely observed in other respiratory viral infections, such as severe lymphopenia and eosinopenia, extensive pneumonia and lung tissue damage, a cytokine storm leading to acute respiratory distress syndrome and multiorgan failure.	./cache/cord-332153-fczf3lzc.txt	./txt/cord-332153-fczf3lzc.txt