id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-332678-yk1stlty	Baldacini, Mathieu	Concomitant haemorrhagic syndrome and recurrent extensive arterial thrombosis in a patient with COVID‐19 and acute promyelocytic leukaemia	2020-05-26		.txt	text/plain	1045	82	43	title: Concomitant haemorrhagic syndrome and recurrent extensive arterial thrombosis in a patient with COVID‐19 and acute promyelocytic leukaemia Acute promyelocytic leukaemia and COVID-19 are two conditions associated with severe coagulopathy. Acute promyelocytic leukaemia and COVID-19 are two conditions associated with severe coagulopathy. We present here the multiple haemostasis abnormalities observed in a patient with concomitant acute promyelocytic leukaemia and COVID-19. We present here the multiple haemostasis abnormalities observed in a patient with concomitant acute promyelocytic leukaemia and COVID-19. Haemostasis analysis showed diffuse intravascular coagulation (DIC) signs: increased prothrombin time (22Á2 s for a laboratory reference of 13Á2), mild decrease of fibrinogen level (1Á93 g/l, normal value 2-4) and major increase in D-dimers (>20 µg/ml, normal value < 0Á5). 5 Recurrent and extensive thrombosis of cerebral arteries was concomitant with haemorrhages as a result of leukaemia-related DIC, COVID-related coagulopathy and severe thrombocytopenia. High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients	./cache/cord-332678-yk1stlty.txt	./txt/cord-332678-yk1stlty.txt