id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-332995-n0zusu52	Gao, Jinrui	Predictive criteria of severe cases in COVID‐19 patients of early stage: A retrospective observational study	2020-09-06		.txt	text/plain	2011	113	48	RESULTS: Multivariable logistic regression analysis showed that the higher level of hypersensitivity C‐reactive protein (OR = 4.77, 95% CI:1.92‐11.87, P = .001), elevated alanine aminotransferase (OR = 6.87, 95%CI:1.56‐30.21, P = .011), and chronic comorbidities (OR = 11.48, 95% CI:4.44‐29.66, P < .001) are the determining risk factors for the progression into severe pneumonia in COVID‐19 patients. CONCLUSION: Early COVID‐19 patients with chronic comorbidities, elevated hs‐CRP or elevated ALT are significantly more likely to develop severe pneumonia as the disease progresses. Through univariate logistic regression models, we found that advanced age (≥65 years old), chronic comorbidities, lymphocytopenia, elevated hs-CRP, increased D-dimer, and elevated levels of ALT were the key risk factors for the progression of COVID-19 patients into their severe stage (Table 3) . Early COVID-19 patients with chronic comorbidities, elevated hs-CRP or increased ALT are significantly more likely to develop severe pneumonia as disease progresses.	./cache/cord-332995-n0zusu52.txt	./txt/cord-332995-n0zusu52.txt