id author title date pages extension mime words sentences flesch summary cache txt cord-333631-vk3h2qau Tsoungui Obama, H. C. J. Preventing COVID-19 spread in closed facilities by regular testing of employees - an efficient intervention in long-term care facilities and prisons 2020-10-14 .txt text/plain 4476 295 54 Methods and findings: Here, the simulation model underlying the pandemic preparedness tool CovidSim 1.1 (http://covidsim.eu/) is extended to investigate the effect of regularly testing of employees in order to protect immobile resident risk groups in closed facilities. Regular screening of all employees by PCR tests provides a significant reduction of COVID-19 cases and related deaths in LTCFs. While the frequency of testing (testing rate) and the quality of tests have noticeable effects, the waiting time for obtaining test results (ranging from 12 up to 96 hours) hardly impacts the outcome. Here, a mathematical model, based on the freely available CovidSIM simulation tool, 59 is adapted to estimate the benefit and economic gain of routine screening for COVID-19 60 infections of employees in LTCFs and retention facilities by PCR tests. We study the impact of testing employees in LTCFs or incarceration facilities to protect 68 immobile risk groups from COVID-19 infections using an extended SEIR model, i.e., by 69 a deterministic compartmental model of ordinary differential equations. ./cache/cord-333631-vk3h2qau.txt ./txt/cord-333631-vk3h2qau.txt