id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-333960-pkpbts7s	Genet, Bastien	COVID-19 in-hospital mortality and use of renin-angiotensin system blockers in geriatrics patients.	2020-09-09		.txt	text/plain	2661	170	58	The aim of this study was to assess the relationship between angiotensin receptor blockers (ARB) and an ACE inhibitor (ACEI) use and in-hospital mortality in geriatric patients hospitalized for COVID-19. In a multivariate Cox regression model including age, sex, ADL score, Charlson index, renal function, dyspnea, CRP and white blood cells count, use of ACEI/ARB was significantly associated with lower in-hospital mortality (HR = 0.52 (0.27−0.99), p=0.048). Conclusion and Implications In very old subjects hospitalized in geriatric settings for COVID-19, mortality was significantly lower in subjects treated with ARB or ACEI prior to the onset of infection. In observational studies, subjects with cardiovascular diseases and hypertension are often 47 treated with ACEI or ARB, and have an increased risk of in-hospital mortality related to COVID-19. In a multivariate Cox regression model including age, sex, ADL, CCI, renal function, dyspnea, 154 CRP and WBC, use of ACEI or ARB was significantly associated with lower in-hospital mortality (HR = 155 0.52 (0.27−0.99), p=0.048) (Figure 2) .	./cache/cord-333960-pkpbts7s.txt	./txt/cord-333960-pkpbts7s.txt