id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334546-izzavogm	Huang, Ian	C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis	2020-07-02		.txt	text/plain	3581	233	48	In the present study, we conducted a systematic review and meta-analysis to investigate the association between several biomarkers, including serum CRP, PCT, D-dimer, and serum ferritin, and the severity of COVID-19. We included research articles in which samples were adult patients with COVID-19 with data for serum CRP, PCT, D-dimer, and serum ferritin, and reported the data based on the presence or absence of clinically validated definitions of mortality, severe COVID-19, ARDS, and intensive care unit (ICU) care. Meta-regression analysis demonstrated that the association between an elevated CRP, PCT, D-dimer, serum ferritin level, and the composite poor outcome was not significantly affected by gender, age, hypertension, cardiovascular disease, diabetes, and COPD (p > 0.05). This meta-analysis showed that elevated serum CRP, PCT, D-dimer, and serum ferritin levels were associated with an increased composite poor outcome that comprises mortality, severe COVID-19, ARDS, and the need for ICU care in patients with COVID-19.	./cache/cord-334546-izzavogm.txt	./txt/cord-334546-izzavogm.txt