id author title date pages extension mime words sentences flesch summary cache txt cord-334814-stswaiep Vogrig, Alberto Causality in COVID-19-associated stroke: a uniform case definition for use in clinical research 2020-08-01 .txt text/plain 1473 98 45 Even if the World Health Organization (WHO) has provided definition for suspected, probable, and confirmed COVID-19 cases, we believe that only patients with laboratory-confirmed SARS-CoV-2 should enter in the classification, in addition to clinic-radiological evidence of acute stroke (ischemic or hemorrhagic). Minor criteria were designed to capture additional evidence of a causal and biologically plausible association: (1) onset of stroke few days to 3 weeks after COVID-19 symptoms [3] [4] [5] ,(2) lack of cardiovascular risk factors [1, 8] ,(3) D-dimer and/or lactate dehydrogenase elevation [3] [4] [5] . Typical clinical features of COVID-19-related stroke include large vessel occlusion, multi-territory involvement, and posterior circulation predisposition (Fig. 1a-g) [3] [4] [5] 8 ]. In particular, case 12 was a previously healthy 50-year-old man who developed a posterior circulation stroke 3 days after the onset of COVID-19 symptoms in the context of vertebral artery dissection [7] , consistent with our proposed definition. ./cache/cord-334814-stswaiep.txt ./txt/cord-334814-stswaiep.txt