id author title date pages extension mime words sentences flesch summary cache txt cord-335465-sckfkciz Gupta, Rishi K. Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: An observational cohort study 2020-09-25 .txt text/plain 5052 246 33 We aimed to address this knowledge gap by systematically evaluating the performance of proposed prognostic models, among consecutive patients hospitalised with a final diagnosis of COVID-19 at a single centre, when using predictors measured at the point of hospital admission. We also assessed the discrimination of each candidate model for standardised outcomes of: (a) our composite endpoint of clinical deterioration; and (b) mortality, across a range of pre-specified time horizons from admission (7 days, 14 days, 30 days and any time during hospital admission), by calculating time-dependent AUROCs (with cumulative sensitivity and dynamic specificity) [18] . In order to further benchmark the performance of candidate prognostic models, we then computed AUROCs for a limited number of univariable predictors considered to be of highest importance a priori, based on clinical knowledge and existing data, for prediction of our composite endpoints of clinical deterioration and mortality (7 days, 14 days, 30 days and any time during hospital admission). ./cache/cord-335465-sckfkciz.txt ./txt/cord-335465-sckfkciz.txt