id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-336924-7xcbtn3q	Borghi, Maria Orietta	Anti-Phospholipid Antibodies in COVID-19 Are Different From Those Detectable in the Anti-Phospholipid Syndrome	2020-10-15		.txt	text/plain	3190	185	48	OBJECTIVE: To evaluate the prevalence and the clinical association of aPL in a large cohort of COVID-19 patients, and to characterize the epitope specificity of anti-β(2)GPI antibodies. aPL in COVID-19 patients are mainly directed against β(2)GPI but display an epitope specificity different from antibodies in antiphospholipid syndrome. The prevalence of COVID-19 patients positive for aCL and anti-b 2 GPI IgG/IgA/ IgM detected by ELISA and CIA is summarized in Table 2 . Again, there was no association between prolonged aPTT and the presence of aPS/PT antibodies nor with thrombotic events in our COVID-19 cohort. Again, there was no association between prolonged aPTT and the presence of aPS/PT antibodies nor with thrombotic events in our COVID-19 cohort. In conclusion, while the medium/high aPL titers with D1 specificity are associated with vascular events in APS, low antibody titers with reactivity against b 2 GPI epitope(s) different from D1 or D4,5 can be found in COVID-19.	./cache/cord-336924-7xcbtn3q.txt	./txt/cord-336924-7xcbtn3q.txt