id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-337629-rwgqkow3	Casale, Manuele	Could nasal irrigation and oral rinse reduce the risk for COVID-19 infection?	2020-08-15		.txt	text/plain	1403	82	43	We advocate the inclusion of SNIs and ethanol oral rinses as additional measures to the current public health measures, to prevent and control the transmission of any respiratory infectious disease, including COVID-19. 9 conducted a pilot, randomized controlled trial of hypertonic SNI and gargling (HSNIG) versus standard care on healthy adults within 48 hours of URTI onset to assess recruitment, acceptability, symptom duration, and viral shedding of a large number of viruses such as rhinovirus, enterovirus, influenza A virus, and coronavirus. To date, there are not any studies which specifically investigated the antiviral activity of chloride salts against coronavirus family in the nasal mucosa cells. Randomized clinical trials on large population are needed to verify the efficacy of SNIs and oral rinses in preventing spread of COVID-19 evaluating the number of episodes, viral load in the nasal cavities, transmission within household contacts, medication consumption, reported illness, school and work absence, and complication rate.	./cache/cord-337629-rwgqkow3.txt	./txt/cord-337629-rwgqkow3.txt