id author title date pages extension mime words sentences flesch summary cache txt cord-338790-rvdoq616 Wang, Xiaowen Be aware of acute kidney injury in critically ill children with COVID-19 2020-08-26 .txt text/plain 2904 155 47 BACKGROUND: Acute kidney injury (AKI) is a common complication of critically ill adult patients with COVID-19. METHODS: By extracting data from electronic medical records, we conducted a retrospective observational study of kidney involvement in confirmed pediatric COVID-19 cases in Wuhan Children's Hospital during the coronavirus outbreak, from January 24 to March 20, 2020. The AWARE (Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology) study, which enrolled ICUs in 32 hospitals in Asia, Australia, Europe, and North America, showed that the overall incidence of AKI in 4683 critically ill children was 26.9%, and the incidence of severe AKI (KDIGO stage 2 or 3) was 11.6% [8, 14] . The correlation between IL-6 titer and serum creatinine level in our patients suggests that cytokine storm might play a more important role in critically ill COVID-19 children with AKI, in addition to the prerenal and intrarenal injuries. ./cache/cord-338790-rvdoq616.txt ./txt/cord-338790-rvdoq616.txt