id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-339459-z22a5yzo	Mackey, Katherine	Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults: A Living Systematic Review	2020-05-15		.txt	text/plain	4132	202	44	PURPOSE: To evaluate, on an ongoing basis, whether use of ACEIs or ARBs either increases risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or is associated with worse COVID-19 disease outcomes, and to assess the efficacy of these medications for COVID-19 treatment. STUDY SELECTION: Observational studies and trials in adults that examined associations and effects of ACEIs or ARBs on risk for SARS-CoV-2 infection and COVID-19 disease severity and mortality. Three studies (33, 36, 37) , which included a total of 8766 patients with COVID-19 and presented analyses adjusted for important confounding factors, had consistent results and provide moderate-certainty evidence that ACEIs or ARBs are not associated with a higher likelihood of positive SARS-CoV-2 test results among symptomatic patients ( Table 1) . Risks and Impact of ACEIs or ARBs in Adults With SARS-CoV-2 Infection REVIEW Annals.org Annals of Internal Medicine other U.S. study included patients with COVID-19 in the New York University health system and examined ICU admission, assisted ventilation, and death as outcomes (37) .	./cache/cord-339459-z22a5yzo.txt	./txt/cord-339459-z22a5yzo.txt