id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-339990-gtbhb24z	Moroni, Francesco	COVID-19 and arterial thrombosis: A potentially fatal combination	2020-10-20		.txt	text/plain	958	86	42	7 While thrombotic and thromboembolic episodes frequently complicate the course of severe infectious diseases, this study, along with similar reports, suggests that several clinical and pathophysiological features differentiate those related to SARS-CoV-2 infection. 9,10 Second, clinical profile of patients who experience these complications is in line with that emerging from similar reports, suggesting that arterial thrombosis events in SARS-CoV-2 infection more frequently involve relatively young males, and occur in large arterial vessels (e.g. the aorta and the mesenteric artery) without significant pre-existing atherosclerotic burden, suggesting a causative mechanism that may be independent of thrombotic superimposition on an unstable atherosclerotic plaque. Third, hemostatic derangements in critically-ill patients usually involve a combination of coagulation pathway alteration, direct platelet consumption or activation, and inflammation-mediated pro-thrombotic state resulting in disseminated intravascular coagulation (DIC). 7 Interestingly, previous reports on venous thromboembolism in severe COVID-19 pneumonia have also showed a substantial rate of thrombotic events in spite of adequate prophylactic anticoagulation 11 . Unusual arterial thrombotic events in Covid-19 patients	./cache/cord-339990-gtbhb24z.txt	./txt/cord-339990-gtbhb24z.txt