id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341175-rks0l0q0	Essa, Musthafa Mohamed	Possible role of tryptophan and melatonin in COVID-19	2020-08-21		.txt	text/plain	817	57	41	4 Until the development of vaccines and better therapeutics, there is an urgent need for strategies to control respiratory infection and to boost immune functions for patients suffering from COVID-19. Dietary fatty acids affecting the pro-inflammatory cytokines have been suggested to affect the metabolic fate of Trp. Tryptophan and its metabolites including melatonin have the capacity to improve the immune system and reduce inflammation in various conditions. [7] [8] [9] Here, we discuss the potential of using tryptophan and its metabolites including melatonin to boost the immune system in fighting COVID-19 infection (see Figure 1) . Increasing evidence from several studies show that tryptophan and its metabolites including melatonin can reduce inflammatory reactions and enhance the immune system. [7] [8] [9] There may also be a possibility that serotonin levels are altered in COVID-19 patients because of mental stress, which suggest a role for Trp in treatment.	./cache/cord-341175-rks0l0q0.txt	./txt/cord-341175-rks0l0q0.txt