id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341300-fkdydf4u	Avendano-Sola, C.	Convalescent Plasma for COVID-19: A multicenter, randomized clinical trial	2020-09-01		.txt	text/plain	3839	212	53	Background: Passive immunotherapy with convalescent plasma (CP) is a potential treatment for COVID-19 for which evidence from controlled clinical trials is lacking. 6 A second trial was also prematurely stopped after a first interim analysis showed that most patients already had high neutralizing antibody titers at the time of inclusion and that no statistical differences in outcomes were seen between treatment groups. 10, 11 Tens of thousands of COVID-19 patients have been treated with CP based on the premise that RCT "take significant time to produce results and will not be available for participation to all hospitals", 10 despite the lack of evidence for efficacy, and the fact that such uncontrolled models lead to questionable estimates of treatment effects. Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial	./cache/cord-341300-fkdydf4u.txt	./txt/cord-341300-fkdydf4u.txt