id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341833-wf72fra8	Liu, Guoqiang	A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment	2020-08-21		.txt	text/plain	2565	149	48	20 A pilot, openlabel, prospective phase 1 clinical trial in HIV-positive patients with Vit D deficiency showed that a single dose of 200,000 IU oral Vit D increased the frequencies of antigen-specific T cells expressing macrophage inflammatory protein 1β (MIP-1β), an important anti-HIV blocking chemokine. In a recent study, 51 HIV-infected youths, with baseline serum 25(OH)D concentrations ≤30 ng/mL, were enrolled and treated by adding three different Vit D doses of 18,000 IU, 60,000 IU and 120,000 IU monthly on a combination antiretroviral therapy. These data suggested that high-dose Vit D supplementation may attenuate immune activation and exhaustion and serve as adjuvant therapy to antiretroviral therapy in HIV-infected people. Low plasma 25(OH) vitamin D level is associated with increased risk of COVID-19 infection: an Israeli population-based study The effect of treatment of vitamin D deficiency on the level of P-selectin and hs-CRP in patients with thromboembolism: a pilot randomized clinical trial	./cache/cord-341833-wf72fra8.txt	./txt/cord-341833-wf72fra8.txt