id author title date pages extension mime words sentences flesch summary cache txt cord-343545-ga56ozp3 Pablos, J. L. Clinical Outcomes of Patients with COVID-19 and Chronic Inflammatory and Autoimmune Rheumatic Diseases: A Multicentric Matched-Cohort Study 2020-06-20 .txt text/plain 3865 250 47 title: Clinical Outcomes of Patients with COVID-19 and Chronic Inflammatory and Autoimmune Rheumatic Diseases: A Multicentric Matched-Cohort Study Methods In this comparative cohort study, we identified hospital PCR+ COVID-19 rheumatic patients with chronic inflammatory arthritis (IA) or autoimmune/immunomediated diseases (AI/IMID). Ageing, male sex and previous comorbidity (obesity, diabetes, hypertension, cardiovascular, or lung disease) increased the risk in the rheumatic cohort by bivariate analysis. Conclusion In patients with chronic inflammatory rheumatic diseases aging, sex and having an AI/IMID but not IA nor previous immunosuppressive therapies were associated with severe COVID-19. We undertook a multicentric comparative cohort study to investigate the relationship between underlying rheumatic disease and COVID-19 outcomes and to identify specific risk factors associated to poor outcomes. In this matched-cohort study, we show that among hospital patients with chronic inflammatory rheumatic diseases, having a systemic AI/IMID but not an IA is an independent risk factor for poor COVID outcomes including death, invasive ventilation, ICU admission or serious complications. ./cache/cord-343545-ga56ozp3.txt ./txt/cord-343545-ga56ozp3.txt