id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344270-874i31h8	Radke, Robert M	Adult congenital heart disease and the COVID-19 pandemic	2020-06-10		.txt	text/plain	4677	273	39	Based on anatomy and additional physiological factors including symptoms, exercise capacity, heart failure, pulmonary hypertension and cyanosis, we propose a pragmatic approach to categorising patients into low-risk, intermediate-risk and high-risk groups. Patients with right heart dilatation or dysfunction are potentially at increased risk of right heart failure as mechanical ventilation and acute respiratory distress syndrome can lead to increase in pulmonary arterial pressures. While this may have ample indirect implications for the regular care of adults with congenital heart disease (ACHD) due to postponement of diagnostic and therapeutic procedures, the focus of the current review is on the direct impact of SARS-CoV-2 on congenital patients. 31 Infection with SARS-CoV-2 should be suspected in ACHD patients presenting with fever, onset or worsening of dyspnoea, lower than usual peripheral oxygen saturation but also in case of unexplained worsening of ventricular function or new arrhythmia. Patients with Down syndrome (commonly associated with congenital heart disease and immune defects) are at higher risk for pulmonary infections and ARDS.	./cache/cord-344270-874i31h8.txt	./txt/cord-344270-874i31h8.txt