id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344375-pr6jlc5c	Emert, Roger	COVID-19 and hypercoagulability in the outpatient setting	2020-05-23		.txt	text/plain	900	49	36	In the inpatient setting, patients with severe SARS-CoV-2 infections leading to pneumonia and hypoxic respiratory failure demonstrate elevated D-dimer and fibrinogen, evidencing a hypercoagulable state [5] . [6] In patients with severe COVID, elevated D-dimer correlated positively with increased 28-day mortality [7] and current guidelines recommend therapeutic anti-Journal Pre-proof J o u r n a l P r e -p r o o f coagulation in the setting of elevated D-dimers, as a high incidence of VTE has been reported on prophylactic dosing [8] . It stands to reason that viral infection from COVID-19, which has demonstrated remarkable elevations in hematological markers of coagulation [12] , would increase this risk further, especially as similar findings were seen in patients with severe acute respiratory syndrome (SARS), a related coronavirus [13] . A recent prospective study of autopsy findings from consecutive deaths from COVID-19 found thromboembolic events to an important feature of mortality, with only a small proportion of patients characterized from the outpatient setting [18] .	./cache/cord-344375-pr6jlc5c.txt	./txt/cord-344375-pr6jlc5c.txt