id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-345356-gn1iwis0	Glebov, Oleg O.	Understanding SARS‐CoV‐2 endocytosis for COVID‐19 drug repurposing	2020-06-02		.txt	text/plain	3502	175	35	Given that most viruses use endocytosis to enter the host cell, mechanistic investigation of SARS‐CoV‐2 infection needs to consider the diversity of endocytic pathways available for SARS‐CoV‐2 entry in the human lung epithelium. Taken together, the above evidence suggests that SARS-CoV-2 may employ distinct endocytic pathways for cell entry in the upper and lower respiratory tract (Fig. 1) . This approach would allow tracking of the virus in relation to other endocytic pathways and also to investigate the effect of viral infection on the general membrane trafficking network of the host cell. Taken together, the combination of adequate cell models with the newly developed SARS-CoV-2 toolkit and established tools of membrane trafficking research is well-poised to deliver a key insight into the mechanisms underlying COVID-19 infection. Furthermore, considering that various viruses may use the same endocytic pathways of the host cell [15] , targeting viral entry at the point of endocytosis holds a more general promise for the development of broad-spectrum antiviral drugs [51] .	./cache/cord-345356-gn1iwis0.txt	./txt/cord-345356-gn1iwis0.txt