id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347186-tbtmqmpr	Acharya, Yogesh	Chloroquine and hydroxychloroquine as a repurposed agent against COVID-19: a narrative review	2020-08-04		.txt	text/plain	3549	200	45	Non-specific combinations of the search strings included (Coronavirus OR Severe Acute Respiratory Syndrome OR SARS OR Chloroquine and hydroxychloroquine as a repurposed agent against COVID-19: a narrative review CQ and HCQ share similar pharmacokinetics, with rapid absorption from the gastro-intestinal surfaces, and are renally and hepatically eliminated. conducted a prospective observational safety study to evaluate the effect of CQ, HCQ, and azithromycin in association with QT interval and risk of TdP and sudden cardiac death in COVID-19 patients. Apart from a general warning, the FDA has cautioned against the indiscriminate use of CQ/ HCQ, either alone or in combination with azithromycin, in COVID-19 patients due to the potential linkage to cardiac toxicities, including severe complications like rhythm disturbances. No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection	./cache/cord-347186-tbtmqmpr.txt	./txt/cord-347186-tbtmqmpr.txt