id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349822-ehidj2ev	Chang, Raymond	Repositioned chloroquine and hydroxychloroquine as antiviral prophylaxis for COVID-19: A protocol for rapid systematic review of randomized controlled trials	2020-04-23		.txt	text/plain	2435	140	48	In this setting, the existing drugs chloroquine (CQ) and hydroxychloroquine (HCQ) which has suggestive evidence of efficacy against SARS-CoV-2 infection and COVID-19 disease has become prime candidates to be repositioned as therapeutic and preventative agents, and a growing number of clinical trials have been registered to study their preventative potential for at-risk populations using a range of dosing schemes and outcome measures. This rapid systematic review protocol aims to provide streamlined and timely synthesis on methodologies and results of randomized controlled trials assessing the efficacy of CQ and HCQ in hopes that this will constructively inform further research as well as public health policy. . https://doi.org/10.1101 /2020 Using standardised forms, two researchers will independently extract data on study design, setting, participant characteristics, intervention and comparison details including dosage, duration, timing and route of administration, outcomes assessed and time of measure, as well as funding source or conflicts of interests as reported by authors of the trials.	./cache/cord-349822-ehidj2ev.txt	./txt/cord-349822-ehidj2ev.txt