id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-350622-8tgxdbyi	Palit, Partha	Phytopharmaceuticals mediated Furin and TMPRSS2 receptor blocking: can it be a potential therapeutic option for Covid-19?	2020-10-28		.txt	text/plain	5083	206	37	Hence, this strategy may limit life-threatening Covid-19 infection and its mortality rate through nano-suspension based intra-nasal or oral nebulizer spray, to treat mild to moderate SARS-COV-2 infection, when Furin and TMPRSS2 receptor may initiate to express and activate for processing the virus to cause cellular infection by replication within the host cell. Drug particle formulated as a harmonious combination of cocktail receptor inhibitors at optimal and pharmacologically relevant dose could block the host cell receptor Furin, and TMPRSS2 receptor located in the target organs like esophagus, lungs, as well as in colon, liver, heart, kidneys, intestine and pancreas to prevent the entry of the SARS-CoV-2. Hence, some selected lead phytopharmaceuticals can primarily be focused on anti-COVID-19 drug discovery and development as mentioned in Table 1 and Table 2 based on their anti-viral activity reported against influenza, HIV, and other RNA viruses through host cell surface receptors ACE2, Furin and TMPRSS2 blocking action.	./cache/cord-350622-8tgxdbyi.txt	./txt/cord-350622-8tgxdbyi.txt