id author title date pages extension mime words sentences flesch summary cache txt cord-351187-kxouck2q Cothran, Thomas P. A Brewing Storm: The Neuropsychological Sequelae of Hyperinflammation due to COVID-19 2020-06-23 .txt text/plain 706 48 30 authors: Cothran, Thomas P.; Kellman, Suzanne; Singh, Shifali; Beck, Jonathan S.; Powell, Karina J.; Bolton, Corey J.; Tam, Joyce W. The goal of this letter is to highlight the importance of understanding and assessing potential COVID-19 neuropsychological sequelae that may result from the effects of hyperinflammation. For severe cases of COVID-19, the effects of cytokine storm syndrome, coagulation disorders, and hypoxia warrant special attention as potential direct and indirect causes of long-term cognitive impairment. Research efforts will need to consider possible iatrogenic complications, as treatments for COVID-19 symptoms, including medications, mechanical ventilation, and prolonged hospitalization, may have unanticipated, adverse effects on cognition. Severe COVID-19 infection triggers a complex inflammatory response that may result in cytokine storm syndrome, stroke, hypoxia, and/or delirium -each a threat to cognitive health. Meanwhile, screening for cognitive changes with possible referral to neuropsychology, monitoring of potential psychiatric symptoms, and recommending rehabilitation services as needed will likely be beneficial as patients continue to recover from COVID-19. ./cache/cord-351187-kxouck2q.txt ./txt/cord-351187-kxouck2q.txt