id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-351662-rmkcb6o3	Huang, Zhifeng	Characteristics and roles of SARS‐CoV‐2 specific antibodies in patients with different severities of COVID‐19	2020-07-24		.txt	text/plain	2855	179	54	We aimed to quantify the levels of SARS‐CoV‐2‐specific IgM, IgA, and IgG antibodies, identify changes in them based on COVID‐19 severity, and establish the significance of combined antibody detection. The rise times for specific IgM and IgG levels are different, and combined detection could be more advantageous in the diagnosis of COVID-19 [5] . In this study, SARS-CoV-2-specific IgM, IgA, and IgG levels were measured in patients with varying severities of COVID-19, the relationship between specific antibody levels and disease severity was classified, and the significance of combined antibody detection was clarified, providing a reference for the clinical diagnosis of COVID-19. We also found that while IgA and IgG levels were significantly higher in the severe & critical patients than in moderate patients, there was no difference in IgM between the two groups. Levels of IgA and IgG were higher in severe & critical COVID-19 patients than in moderate COVID-19 patients, while IgM levels were no different between the two groups.	./cache/cord-351662-rmkcb6o3.txt	./txt/cord-351662-rmkcb6o3.txt