id author title date pages extension mime words sentences flesch summary cache txt cord-351762-n95ar9ci Wang, Brian Xiangzhi Susceptibility and prognosis of COVID-19 patients with cardiovascular disease 2020-06-25 .txt text/plain 1496 88 48 1 Here, we outline what is known about the susceptibility of patients with CVDs to COVID-19 and the relative risk of these patients succumbing to severe illness. dIsease transmIssIon COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), phylogenetically related to the beta coronavirus SARS that caused a global outbreak in 2002. Importantly, this study also supported the notion that patients with CVDs were more likely to suffer severe illnesses from COVID-19 infection-10.5% of patients with CVDs and 6.0% with hypertension died, compared with the 0.9% in patients with no comorbidities. 10 This led to growing concerns that medications acting on the renin-angiotensin-aldosterone system increased the risk of patients contracting COVID-19 or having a more severe illness. 11 A population-based study by Mancia and colleagues on patients in Lombardy, Italy, identified that ACEIs and ARBs were more frequent in patients with COVID-19 than controls, attributed to the higher prevalence of cardiovascular disease. ./cache/cord-351762-n95ar9ci.txt ./txt/cord-351762-n95ar9ci.txt