id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-352678-8f2ygul2	Prasad, Ashish	Single Virus Targeting Multiple Organs: What We Know and Where We Are Heading?	2020-08-05		.txt	text/plain	3488	191	48	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causal agent of Coronavirus disease 2019 (COVID19) , is a single-stranded RNA virus with a non-segmented genome. In another study with COVID-19 patients in China, an early response of IgA instead of IgG was observed in the humoral immune response against SARS-CoV-2 (11) . It has been observed that 5% of COVID-19 patients become critically ill with severe pneumonia and multiple-organ damage and cytokine storm might be a possible explanation for such an observation. A case study on 214 COVID-19 patients from three special care centers of Union Hospital, Wuhan, revealed that 36.4% of the infected people had neurologic symptoms (46) . The adverse effects of antiviral drugs like hydroxychloroquine, which is reported to cause acute toxic hepatitis (54) and cytokine burst, might be responsible for such high percentage of hepatic damage cases in severely ill patients.	./cache/cord-352678-8f2ygul2.txt	./txt/cord-352678-8f2ygul2.txt