id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-352700-8ic7gu5y	Hernandez Cordero, A. I.	Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19	2020-10-06		.txt	text/plain	4269	266	55	We used Bayesian colocalization (COLOC) and summary-based Mendelian randomization to combine gene expression quantitative trait loci (eQTLs) from the Lung eQTL (n=1,038) and eQTLGen (n=31,784) studies with published COVID-19 genome-wide association study (GWAS) data from the COVID-19 Host Genetics Initiative. 2018 We first conducted Coloc tests to determine the probability that SNPs associated to COVID-252 19 phenotypes and gene expression (eQTLs) were consistent with shared genetic causal 253 variants (colocalization). The colocalization between ABO gene expression and the 383 COVID-19 susceptibility associated loci was not tested since the variants associated with 384 this gene in the lung eQTL and eQTLGEN studies were not present in the COVID-19 HG 385 meta-analysis for this phenotype. In blood, the expression of 18 and 8 unique genes co-localized with COVID-19 severity 388 ( Fig. 2a) and susceptibility associated loci (Supplementary Table S1), respectively.	./cache/cord-352700-8ic7gu5y.txt	./txt/cord-352700-8ic7gu5y.txt